Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain
![Research Highlight - An Activity-Based Fluorescent Probe for Imaging Fluctuations of Peroxynitrite (ONOO-) in the Alzheimer's Disease Brain](http://chem.korea.ac.kr/files/attach/images/152/718/015/4dc8e896bb53cacf525483b8602b9629.png)
Peroxynitrite (ONOO-) plays a critical role in Alzheimer's disease (AD), and the association between ONOO- and AD is inexplicit. To reveal the ONOO- influxes in AD brains, an activatable activity-based fluorescence probe Rd-DPA3 was rationally designed by a structure-modulated strategy. Taking advantage of ONOO--sparked two-step cascade reactions of a novel chemical trigger, Rd-DPA3 specifica
![](https://pubs.acs.org/cms/10.1021/acs.analchem.3c01447/asset/images/medium/ac3c01447_0008.gif)
Near-Infrared Fluorescent Probe for the In Situ Visualization of
Activatable Near-Infrared Fluorescent and Photoacoustic Dual-Modal
![](https://pub.mdpi-res.com/targets/targets-01-00003/article_deploy/html/images/targets-01-00003-g007.png?1685607030)
Targets, Free Full-Text
![](https://ars.els-cdn.com/content/image/1-s2.0-S0010854521006305-gr26.jpg)
Activity-based fluorescence probes for pathophysiological
![](https://media.springernature.com/lw685/springer-static/image/art%3A10.1186%2Fs40779-023-00467-7/MediaObjects/40779_2023_467_Fig2_HTML.png)
Activatable fluorescent probes for imaging and diagnosis of
![](https://pubs.rsc.org/image/article/2023/CS/d2cs00172a/d2cs00172a-f15.gif)
Recent progress in the development of fluorescent probes for
Near-Infrared Fluorescent Probes as Imaging and Theranostic
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs40779-023-00467-7/MediaObjects/40779_2023_467_Fig5_HTML.png)
Activatable fluorescent probes for imaging and diagnosis of
![](https://ars.els-cdn.com/content/image/1-s2.0-S014372082300311X-gr21.jpg)
Recent progress in rational design of peroxynitrite fluorescent
![](https://pub.mdpi-res.com/molecules/molecules-27-07750/article_deploy/html/images/molecules-27-07750-g004.png?1668084542)
Molecules, Free Full-Text
![](https://ars.els-cdn.com/content/image/1-s2.0-S000326701931428X-fx1.jpg)
An efficient TP-FRET-based lysosome-targetable fluorescent probe
![](https://onlinelibrary.wiley.com/cms/asset/41741990-ba59-4d67-8679-4c50b361d39f/anie202206894-fig-0006-m.jpg)
An Activity‐Based Fluorescent Probe for Imaging Fluctuations of