A more complete NO/ONOO- cycle diagram. Central to the figure are the
Download scientific diagram | A more complete NO/ONOO- cycle diagram. Central to the figure are the reciprocal interactions between peroxynitrite, abbreviated as PRN and tetrahydrobiopterin (BH4) depletion. Also indicated is the ATP depletion produced by peroxynitrite, superoxide and nitric oxide. And in the upper left corner, TRP represents the three TRP receptors, TRPV1, TRPA1 and TRPM2, each of which is stimulated via distinct mechanisms by oxidative stress. Each arrow in the figure represents one or more mechanisms by which one element of the cycle stimulates another element of the cycle. Figure and legend is taken from the author’s web site with permission. from publication: The NO/ONOO-Vicious Cycle Mechanism as the Cause of Chronic Fatigue Syndrome/Myalgic Encephalomyelitis | Cases of chronic fatigue syndrome/mylagic encephalomyelitis (CFS) are reported to be initiated by nine different short-term stressors, each of which increase levels of nitric oxide in the body. Elevated nitric oxide, acting through its oxidant product, peroxynitrite, | Chronic Fatigue Syndrome, Clinical Protocols and Clinical Studies | ResearchGate, the professional network for scientists.
Molecular and metabolic orchestration of the lymphatic vasculature in physiology and pathology
Role of neuroinflammation in neurodegeneration development
Nitric Oxide Releasing Delivery Platforms: Design, Detection, Biomedical Applications, and Future Possibilities
Frontiers The old second messenger cAMP teams up with novel cell death mechanisms: potential translational therapeutical benefit for Alzheimer's disease and Parkinson's disease
A more complete NO/ONOO- cycle diagram. Central to the figure are the
IJMS, Free Full-Text
Emerging early diagnostic methods for acute kidney injury
Frontiers Nitric oxide: A core signaling molecule under elevated GHGs (CO2, CH4, N2O, O3)-mediated abiotic stress in plants
Redox-dependent regulation of the Na+–K+ pump: New twists to an old target for treatment of heart failure - Journal of Molecular and Cellular Cardiology